Revelation 15:2
KJV
And I saw as it were a sea of glass mingled with fire: and them that had gotten the victory over the beast, and over his image, and over his mark, and over the number of his name, stand on the sea of glass, having the harps of God.
NIV
And I saw what looked like a sea of glass glowing with fire and, standing beside the sea, those who had been victorious over the beast and its image [omit] and over the number of its name. They held harps given them by God
If the mark ends up being a biological implant that affects the humanity of men (probably making it an abomination to God), it would be highly significant to mention that victory was obtained over it. See also: Rev 13:16, 14:9
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